Prenatal Testing

Prenatal care is essential to ensure the healthy growth and development of a fetus. Women who receive prenatal care have healthier babies, are less likely to deliver prematurely, and have fewer pregnancy-related problems. Prenatal care should begin as early as possible. Doctor visits are usually monthly, and become more frequent as the pregnancy progresses. Routine tests at these visits include urine testing and blood-pressure checks. In addition to routine tests, there are several prenatal tests that are performed at specific times during the pregnancy. They are administered to monitor the health of the fetus and, in some cases, the mother.

Types of Prenatal Tests

A variety of prenatal tests are performed to monitor the fetus's health, and identify anything that can lead to complications. Certain tests are administered at different times throughout the pregnancy. After initial blood and urine tests to confirm a pregnancy, additional prenatal tests often include those below.

Cell-Free DNA Testing

Cell-free DNA testing is a noninvasive way of testing a fetus's DNA by using the mother's blood. It can be performed at 10 weeks of pregnancy, and is used to determine whether the fetus has a genetic condition such as Down syndrome. It is usually only recommended if a previous ultrasound has detected a birth defect, or the woman already has a child with a genetic condition or birth defect.

Chorionic Villus Sampling

Chorionic villus sampling (CVS) is commonly performed at 10 to 12 weeks of pregnancy. It is used to determine whether the fetus has a genetic condition such as Down syndrome. During the test, a sample of chorionic villi is removed from the placenta for testing. An ultrasound may be performed in conjunction with this test to guide the physician as the tissue sample is removed.

Alpha-Fetoprotein Test

The alpha-fetoprotein (AFP) test examines the level of alpha-fetoprotein in the mother's blood during pregnancy. This test is commonly performed between the 14th and 18th weeks of pregnancy. A blood sample is taken from the mother to measure the AFP levels in her blood, which may be an indicator of certain genetic conditions or birth defects.


A fetal ultrasound (sonogram) is an imaging technique that produces images of the fetus. This test is commonly performed at 18 to 20 weeks of pregnancy. Fetal ultrasound images help to monitor the fetus's growth and development, and determine how the pregnancy is progressing.

Nuchal Translucency Screening

Nuchal translucency screening is commonly performed at 11 to 14 weeks of pregnancy. An ultrasound is used to measure the thickness of the back of the fetus's neck. The information obtained from the ultrasound, in conjunction with a blood test, is used to determine whether Down syndrome is present.


Amniocentesis is commonly performed at 15 to 20 weeks of pregnancy to determine whether the fetus has Down syndrome or another genetic condition. During the test, a thin needle is inserted into the mother's abdomen to suction out a small amount of tissue and cells from the amniotic fluid that surrounds the fetus. It is usually only performed if the mother has a high risk of having a child with a genetic condition, or is at an advanced age for pregnancy.

Glucose Screening

Glucose screening is normally performed at 24 to 28 weeks of pregnancy; it is used to test for gestational diabetes. The mother consumes a sugary drink, and her blood is tested an hour later to measure her blood-sugar levels.

Group B Streptococcus Infection Screening

Group B Streptococcus infection screening is often performed at 35 to 37 weeks of pregnancy. It is used to determine the presence of any streptococcus bacteria, which can cause serious infections in the fetus. Swabs are used to take samples from the mother's vagina and rectum. A woman who tests positive for this bacteria will need antibiotics when she is in labor.

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